Figure 6. Rate of perceived exertion recorded at 10-min intervals during exercise and at the voluntary termination of exercise by subjects with lower (A) and higher (B) aerobic capacity. Each subject participated in four experimental trials with the following drug conditions: placebo and 10, 20 and 40 mg of paroxetine. The data are expressed as the median. & denotes that the results of the 40 mg paroxetine trial were significantly different from those of the 10 mg paroxetine and placebo trials (p < 0.05). # denotes that the results of the 20 mg paroxetine trial were significantly different from those of the placebo trial (p < 0.05). a denotes significant differences relative to the respective control trial in the subjects with lower aerobic capacity for the 40 mg paroxetine trial (p < 0.05). b denotes significant differences relative to the respective control trial in the subjects with lower aerobic capacity for the placebo, 20 mg paroxetine and 40 mg paroxetine trials (p < 0.05). c denotes significant differences relative to the respective control trial in subjects with lower aerobic capacity for all trials (p < 0.05).