Figure 3. Effects of 12-week physical exercise and high triglyceride diet on heme oxygenase activity in the aorta. Changes in HO-1 activity (expressed as nmol/h/mg protein) are expressed as means ± SEM (n = 8-9). Statistical significance: â—‹â—‹â—‹â—‹ p < 0.0001 as compared to SO CTRL NR group and # p < 0.05, #### p < 0.0001 a significant difference between non-running (NR) and running (R) animals. SO = sham-operated, OVX = ovariectomized, CTRL= standard chow, HT = high-triglyceride, NR= non-running, R = running.