Figure 5. Effects of 12-week physical exercise and high triglyceride diet on cardiac HO activity. Changes in HO activity (expressed as nmol/h/mg protein) are expressed as means ± SEM (n = 6-9). Statistical significance: â—‹â—‹â—‹â—‹ p < 0.0001 as compared to SO CTRL NR group and #### p < 0.0001 a significant difference between non-running (NR) and running (R) animals. SO = sham-operated, OVX = ovariectomized, CTRL = standard chow, HT = high-triglyceride, NR= non-running, R = running.