Figure 1. Experimental design and protocol for 8 weeks treadmill exercise training. Eight weeks old, male, wistar rats were assigned to sedentary control (Control) and training groups which are divided into 3 groups contained 5 rats each group : Low Intensity (LI), Moderate Intensity (MI), and High Intensity (HI) and given 8 weeks treadmill exercise following procedure established by Lesmana et al. 2016 with small modification. The pre-Exercise (Habituation) period lasted for 2 weeks.