Table 1. Demographic and clinical characteristics. Data are means (± SD).
| Patient characteristics |
Normals |
CHF |
p value |
| N |
13 |
46 |
|
| Age (years) |
51 (11) |
63 (12) |
.001 |
| Height (m) |
1.72 (.1) |
1.73 (.1) |
.81 |
| Weight (kg) |
76 (14) |
89 (23) |
.06 |
| Ejection Fraction (%) |
56.5 (9.0) |
42.5 (17.0) |
.007 |
| Peak VO2 (ml·kg-1·min-1) |
24.8 (6.2) |
15.9 (5.6) |
<.001 |
| CHF Etiology, # subjects (%) |
- |
|
- |
| Ischemic Cardiomyopathy |
- |
19 (41) |
- |
| Idiopathic Dilated Cardiomyopathy |
- |
1 (2) |
- |
| CHF with Normal EF* |
- |
18 (39) |
- |
| NYHA Classification, # (%) |
| Class I |
- |
11 (24) |
- |
| Class II |
- |
5 (11) |
- |
| Class III |
- |
24 (52) |
- |
| Class IV |
- |
6 (13) |
- |
| Medications, # subjects (%) |
| Digoxin |
- |
3 (6) |
- |
| Beta Blocker |
6 (46) |
35 (76) |
.11 |
| ACE/ARB |
5 (38) |
26 (57) |
<.001 |
CHF=chronic heart failure; EF=ejection fraction; NYHA=New York Heart Association; ACE/ARB=ACE inhibitor/angiotensin receptor blocker *>45%
