Muscle Fiber Specific Antioxidative System Adaptation to Swim Training in Rats: Influence of Intermittent Hypoxia

Table 2. State of glutathione system and activity of glucose-6-phosphate dehydrogenase in skeletal muscle after acute and chronic exercise, and also after different regimes of intermittent hypoxic training (n = 10). Data are means (±SEM).

Groups	GSH		GPx
Control
	1 2	1.20 (.08) .79 (.03)	6.43 (.31) 4.66 (.20)	6.86 (.62) 4.16 (.27)	1.98 (.09) 2.21 (.12)
Acute exercise (30 min)
	1 2	.90 (.04) ** .54 (.05) *	5.00 (.18) * 3.42 (.20) *	5.04 (1.01) 3.27 (.38)*	2.19 (.10) 3.88 (.20) **
Chronic exercise (4 wk)
	1 2	1.26 (.04) .84 (.07)	6.50 (.46) 5.93 (.24) **	8.17 (.87)* 5.45 (.15)*	2.60 (.13) 3.45 (.15)
IHT (2 wk)
	1 2	1.58 (.10) * 1.16 (.09) **	8.36 (.78) * 6.85 (.46) **	10.82 (2.0)** 6.03 (.40) *	2.32 (.10) * 3.11 (.12) **
Chronic exercise (4wk) + IHT during the first two weeks
	1 2	1.39 (.06) # .90 (.06) #	7.59 (.36) *# 6.05 (.30) #	9.62 (.05) # 7.00 (.62) #	2.16 (.09) 2.43 (.12) #
Chronic exercise (4 wk) + IHT during the last two weeks
	1 2	1.46 (.09) # .98 (.04) #	7.88 (.41) # 6.42 (.24) *	9.83 (1.06)# 6.90 (.40) #	2.20 (.10) 2.35 (.10) #

Abbreviations: GSH= reduced glutathione (µmol·mg protein-1), GR= glutathione reductase (nmol NADPH·min-1·mg protein-1), GPx= glutathione peroxidase (µmol GSH·mg protein-1), G6PDH= glucose-6-phosphate dehydrogenase (nmol NADPH·min-1· mg protein-1), IHT= intermittent hypoxic training. 1) red gactrocnemius/soleus muscles, 2) white gasrtrocnemius muscle.* p < 0.05 compared with control,** p < 0.01 compared with control;# p < 0.05 compared with chronic exercise.