Table 3. Genotypic distribution and relative allelic frequencies for the studied polymorphisms.
Gene / Polymorphism |
Genotypes % (n) |
Alleles |
H-W |
ACE / rs1799752 |
I/I: 39.1(75) |
I/D: 44.8(86) |
D/D: 16.1(31) |
I: 0.62 |
D: 0.38 |
χ2 = 0.6; 1 df, p = 0.75 |
5HTT / 5HTTLPR |
L/L: 23.4(45) |
L/S: 43.2(83) |
S/S: 33.4(64) |
L: 0.45 |
S: 0.55 |
χ2 = 3.1; 1 df, p = 0.21 |
CRF-BP / CRF-BPs11 |
C/C: 35.9(69) |
C/T: 43.8(84) |
T/T: 20.3(39) |
C: 0.58 |
T: 0.42 |
χ2 = 2.0; 1 df, p = 0.36 |
CRF2R / rs2267717 |
G/G: 55.2(106) |
G/A: 35.9(69) |
A/A: 8.9(17) |
G: 0.73 |
A: 0.27 |
χ2 = 1.4; 1 df, p = 0.50 |
5HT1AR / -1019C>G |
C/C: 30.2(58) |
C/G: 48.4(93) |
G/G: 21.4(41) |
C: 0.54 |
G: 0.46 |
χ2 = 0.1; 1 df, p =0.94 |
NK1R / rs6715729 |
A/A: 33.3(64) |
A/G: 45.3(87) |
G/G: 21.4(41) |
A: 0.56 |
G: 0.44 |
χ2 = 1.2; 1 df, p = 0.53 |
H-W= Hardy-Weinberg Equilibrium (Number in parenthesis indicates number of individuals from the total population studied).