Table 3. Association analysis of the IL1B gene rs1143627 polymorphism with ACL rupture.
Model |
ACLR (n=229) |
% |
CON (n=194) |
% |
OR |
95% CI |
p* |
Codominant |
A/A |
99 |
43.2 |
94 |
48.5 |
1.00 |
|
|
0.208/0.377 |
A/G |
101 |
44.1 |
85 |
43.8 |
0.89 |
0.59 |
1.33 |
G/G |
29 |
12.7 |
15 |
7.7 |
0.54 |
0.27 |
1.08 |
Dominant |
A/A |
99 |
43.2 |
94 |
48.5 |
1.00 |
|
|
0.283/0.366 |
A/G-G/G |
130 |
56.8 |
100 |
51.5 |
0.81 |
0.55 |
1.19 |
Recessive |
A/A-A/G |
200 |
87.3 |
179 |
92.3 |
1.00 |
|
|
0.094/0.197 |
G/G |
29 |
12.7 |
15 |
7.7 |
0.58 |
0.30 |
1.11 |
Overdominant |
A/A-G/G |
128 |
55.9 |
109 |
56.2 |
1.00 |
|
|
0.952/0.898 |
A/G |
101 |
44.1 |
85 |
43.8 |
0.99 |
0.67 |
1.45 |
* after a slash p value adjusted for sex; OR – odds ratio, 95% CI – confidence intervals