Table 3. Allelic frequencies of the SNPs identified by comparison between elite endurance runners and controls.
References SNP Frequency of allele in elite endurance runners, % Frequency of
allele in controls, %		 P-value
Ahmetov et al., 2015 NFIA-AS2 rs1572312 C
TSHR rs7144481 C
RBFOX1 rs7191721 G		 95.5
25.7
58.6		 88.8
17.4
56.3		 0.007*
0.032*
0 .60
Amir et al., 2007 ACE D rs4646994
ACE DD rs4646994		 77.0
62.0		 66.0
43.0		 0.01*
0.004*
Ash et al., 2011 ACE I/D rs4646994
ACE A22982G rs4363		 44.7
44.7		 45.6
45.8		 0.16
0.97
Döring et al., 2010 HIF1A Pro582 rs11549465 C
HIF1A rs17099207 A
HIF1A rs1951795 C
HIF1A rs11158358 C/G
HIF1A rs2301113 A/C
HIF1A rs11549467 G/A		 84.0
9.2
67.7
25.3
33.5
3.2		 75.0
4.9
62.2
27.0
32.9
1.6		 0.017*
0.045*
0.038*
0.07
0.06
0.21
He et al., 2015 PPARAGC1A rs4452416 T
PPARAGC1B rs2161257 G
NRF1 rs7794909 T
SIRT1 rs11596401 C		 17.2
39.6
9.6
87.2		 13.1
33.6
5.8
83.3		 0.035*
0.026*
0.007*
0.050*
Martinez et al., 2009 AQP1 rs1049305 C 57.0 49.0 0.03*
Myerson et al., 1999 ACE I rs4646994 52.0 49.0 0.01*
Sawczuk et al., 2013 ADRA2A rs553668 C 85.8 82.9 0.40
Tobina et al., 2010 ACE I/D rs4646994 44.0 44.0 0.001*
Wolfarth et al., 2008 NOS3 Glu298Asp rs1799983 G/T
NOS3 (CA)n repeats 164 bp
NOS3 27-bp repeats 4B/4A		 41.0
24.1
25.0		 47.0
16.7
25.0		 0.27
0.01*
0.83
*Significant difference between elite endurance, including marathon runners, and controls at p < 0.05 level.