 |
| |
| Gene / Variant | Genotype Frequency (%) | H-W | Allele Frequency (%) | |||
|---|---|---|---|---|---|---|
| ACE I/D | I/I | I/D | D/D | I | D | |
| Total (192) | 39.1(75) | 44.8(86) | 16.1(31) | 0.62(119) | 0.38(73) | |
| SP (92) | 54.3(50) | 38.0(35) | 7.6(7) | χ2=0.06; p=0.799 |
0.73(135) | 0.27(49) |
| IP (100) | 25.0(25) | 51.0(51) | 24.0(24) | χ2=0.04; p=0.841 |
0.51(101) | 0.49(99) |
| χ2 = 20.34 ; 2 df; p = 0.006 |
χ2 = 21.16; 1 df; p = 0.0001 |
|||||
| OR: 2.701 (C.I. 95% = 1.759 – 4.146) P = 0.0001 |
||||||
| 5HTT / 5HTTLPR | S/S | S/L | L/L | S | L | |
| Total (192) | 23.4(45) | 43.2(83) | 33.4(64) | 0.45(86) | 0.55(106) | |
| SP (92) | 33.7(31) | 40.2(37) | 26.1(24) | χ2=3.36; p=0.066 |
0.54(99) | 0.46(85) |
| IP (100) | 14.0(14) | 46.0(46) | 40.0(40) | χ2=0.02; p=0.894 |
0.37(74) | 0.63(126) |
| χ2 = 11.08; 2 df; p = 0.004 |
χ2 = 10.93; 1 df; p = 0.001 |
|||||
| OR: 1.983 (C.I. 95% = 1.318 –2.982) P = 0.001 |
||||||
| CRF-BP / CRF-BPs11 | C/C | C/T | T/T | C | T | |
| Total (192) | 35.9(69) | 43.8(84) | 20.3(39) | 0.58(111) | 0.42(81) | |
| SP (92) | 44.6(41) | 41.3(38) | 14.1(13) | χ2=0.70; p=0.390 |
0.65(120) | 0.35(64) |
| IP (100) | 28.0(28) | 46.0(46) | 26.0(26) | χ2=0.60; p=0.4258 |
0.51(102) | 0.49(98) |
| χ2 = 7.22; 2 df; p = 0.027 |
χ2 = 7.94; 1 df; p = 0.005 |
|||||
| OR: 1.801 (C.I. 95% = 1.194 – 2.717) P = 0.005 |
||||||
| CRF2R / rs2267717 | C/C | C/G | G/G | C | G | |
| Total (192) | 55.2(106) | 35.9(69) | 8.9(17) | 0.73(140) | 0.27(52) | |
| SP (92) | 10.9(10) | 37.0(34) | 52.1(48) | χ2=1.09; p=0.296 |
0.20(37) | 0.80(153) |
| IP (100) | 7.0(7) | 35.0(35) | 58.0(58) | χ2=0.29; p=0.589 |
0.17(32) | 0.83(162) |
| χ2 = 1.16; 2 df; p = 0.561 |
χ2 = 1.15; 1 df; p = 0.2841 |
|||||
| OR: 1.280 (C.I. 95% = 0.814 – 2.012) P = 0.447 |
||||||
| 5HT1AR / -1019C>G | C/C | C/G | G/G | C | G | |
| Total (192) | 30.2(58) | 48.4(93) | 21.4(41) | 0.54(104) | 0.46(88) | |
| SP (92) | 43.5(40) | 44.6(41) | 12.0(11) | χ2=0.01; p=0.921 |
0.66(121) | 0.34(63) |
| IP (100) | 18.0(18) | 52.0(52) | 30.0(30) | χ2=0.30; p=0.581 |
0.44(88) | 0.56(112) |
| χ2 = 18.15 ; 2 df; p = 0.0001 |
χ2 = 18.3; 1 df; p = 0.0001 |
|||||
| OR: 2.444 (C.I. 95% = 1.617-3.694) P = 0.0001 |
||||||
| NK1R / rs6715729 | A/A | A/G | G/G | A | G | |
| Total (192) | 33.3(64) | 45.3(87) | 21.4(41) | 0.56(108) | 0.44(84) | |
| SP (92) | 43.5(40) | 37.0(34) | 19.6(18) | χ2=4.29; p=0.038 |
0.62(114) | 0.38(70) |
| IP (100) | 24.0(24) | 53.0(53) | 23.0(23) | χ2=0.36; p=0.547 |
0.51(101) | 0.49(99) |
| χ2 = 8.44 ; 2 df; p = 0.015 |
χ2 = 6.02; 1 df; p = 0.014 |
|||||
| OR: 1.596 (C.I. 95% = 1.063 – 2.397) P = 0.024 |
||||||