Table 7. Association analysis of the IL1B x IL6R interaction with ACL rupture (codominant model).
| IL1B x ILR |
IL6R (rs2228145) |
p vs CON* |
| A/A |
A/C |
C/C |
| ACLR |
CON |
OR |
95% |
CI |
ACLR |
CON |
OR |
95% |
CI |
ACLR |
CON |
OR |
95% |
CI |
| IL1B (rs16944) |
G/G |
46 |
39 |
1.00 |
NA |
NA |
36 |
37 |
1.21 |
0.65 |
2.27 |
17 |
13 |
0.90 |
0.39 |
2.09 |
0.987/
0.991 |
| A/G |
39 |
31 |
0.94 |
0.50 |
1.77 |
48 |
37 |
0.91 |
0.50 |
1.66 |
14 |
9 |
0.76 |
0.30 |
1.94 |
| A/A |
14 |
8 |
0.67 |
0.26 |
1.77 |
10 |
5 |
0.59 |
0.19 |
1.87 |
5 |
2 |
0.47 |
0.09 |
2.57 |
* after a slash p value adjusted for sex; OR – odds ratio, 95% CI – confidence intervals; NA – not applicable
