Review article - (2006)05, 172 - 181
Leptin, its Implication in Physical Exercise and Training: A Short Review
Anissa Bouassida1, Dalenda Zalleg1, Semi Bouassida2, Monia Zaouali1, Youssef Feki3, Abdelkarim Zbidi1, Zouhair Tabka1,
1Laboratory of Cardio-Circulatory, Respiratory, Metabolic and Hormonal Adaptations to the Muscular Exercise, Faculty of Medicine Ibn El Jazzar, 4002 Sousse, Tunisia
2Laboratory of Physiology, ISSEP Ksar-Saîd, Tunis, Tunisia
3Laboratory of Measurements Sciences, ISSEP Kef, Tunisia

Zouhair Tabka
✉ Laboratoire de Physiologie, Faculté de Médecine Ibn El Jazzar, avenue Mohamed Karoui 4002, Sousse, Tunisie.
Email: zouhair.tabka@rns.tn
Received: 28-11-2005 -- Accepted: 22-03-2006
Published (online): 01-06-2006

ABSTRACT

Leptin, a hormone synthesized by fat tissue had been noted to regulate energy balance and metabolism and thus to influence body weight. The influence of acute exercise and chronic exercise training on circulating leptin and its relationship with hormonal and metabolic changes that induce energy balance are presented. Research that has examined the influence of exercise under various experimental conditions on leptin and the conflicts in the literature are presented. It appears that a significant caloric perturbation (> 800 kcals) is necessary for acute exercise to result in a significant reduction in leptin. In contrast, exercise training can result in a leptin decline but typically this manifests a reduction in adipose tissue stores. In addition, future directions are presented.

Key words: Leptin, exercise, training, hormones

Key Points
  • Physical exercise and training have both inhibitory and stimulatory effects on leptin.
  • Exercise with energy expenditure higher than 800 kcal can decrease leptinemia.
  • Acute training may cause a decline in circulating leptin levels.








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