Table 2. State of glutathione system and activity of glucose-6-phosphate dehydrogenase in skeletal muscle after acute and chronic exercise, and also after different regimes of intermittent hypoxic training (n = 10). Data are means (±SEM). Groups GSH GR GPx G6PDH Control 1 2 1.20 (.08) .79 (.03) 6.43 (.31) 4.66 (.20) 6.86 (.62) 4.16 (.27) 1.98 (.09) 2.21 (.12) Acute exercise (30 min) 1 2 .90 (.04) ** .54 (.05) * 5.00 (.18) * 3.42 (.20) * 5.04 (1.01) 3.27 (.38)* 2.19 (.10) 3.88 (.20) ** Chronic exercise (4 wk) 1 2 1.26 (.04) .84 (.07) 6.50 (.46) 5.93 (.24) ** 8.17 (.87)* 5.45 (.15)* 2.60 (.13) ** 3.45 (.15) ** IHT (2 wk) 1 2 1.58 (.10) * 1.16 (.09) ** 8.36 (.78) * 6.85 (.46) ** 10.82 (2.0)** 6.03 (.40) * 2.32 (.10) * 3.11 (.12) ** Chronic exercise (4wk) + IHT during the first two weeks 1 2 1.39 (.06) *# .90 (.06) *# 7.59 (.36) *# 6.05 (.30) # 9.62 (.05) *# 7.00 (.62) *# 2.16 (.09) 2.43 (.12) # Chronic exercise (4 wk) + IHT during the last two weeks 1 2 1.46 (.09) *# .98 (.04) *# 7.88 (.41) *# 6.42 (.24) ** 9.83 (1.06)*# 6.90 (.40) *# 2.20 (.10) 2.35 (.10) # Abbreviations: GSH= reduced glutathione (µmol·mg protein-1), GR= glutathione reductase (nmol NADPH·min-1·mg protein-1), GPx= glutathione peroxidase (µmol GSH·mg protein-1), G6PDH= glucose-6-phosphate dehydrogenase (nmol NADPH·min-1· mg protein-1), IHT= intermittent hypoxic training. 1) red gactrocnemius/soleus muscles, 2) white gasrtrocnemius muscle. * p < 0.05 compared with control, ** p < 0.01 compared with control; # p < 0.05 compared with chronic exercise.