Table 1. Exercise intervention studies in children and adolescents.
Reference Participants Design Intervention Results*
Prepubertal Bradney et al., 1998 Boys. White.
Age 10.4±0.2yrs
Randomized by school
Con = 20; Ex = 20
After school clubs of aerobics, soccer, volleyball, dance, gymnastics, basketball and weight training; 3 times/week; 30mins/session; 8 months duration TB + 2.6% aBMD
LS + 4.3% aBMD
FS + 9.3% BMC
FS + 9.1% vBMD
Mckay et al., 2000 Girls & boys. White & Asian.
Age 8.9±0.7yrs
Randomized by school
Con = 81; Ex = 63
10 tuck jumps prior to class, 3 times/week
Jumping, skipping, hopping 2 times/week
10-30mins/session; 8 months duration
GT + 4.4% aBMD
Fuchs et al., 2001 Girls & boys. White.
Age 7.5±0.2yrs
Randomized within school
Con = 44; Ex = 45
100 two footed drop jumps off 61cm box; GRF = 8.8 bw; 3 times/week; 10mins/session; 7 months duration LS + 2% aBMD
FN + 1.4% aBMD
LS + 3.1% BMC
FN + 4.5% BMC
Mackelvie et al., 2001 Girls. White & Asian.
Age 10.1±0.5yrs
Randomized by school
Con = 26; Ex = 44
50-100 jumps and circuit training GRF = 3.5-5 bw; 3 times/week; 10-12mins/session; 7 months duration NS
Mackelvie et al., 2002 Boys.White & Asian.
Age 10.3±0.6yrs
Randomized by school
Con = 60; Ex = 61
50-100 jumps and circuit training GRF = 3.5-5 bw;
3 times/week; 10mins/session; 7 months duration
PF + 1.6% aBMD
TB + 1.6% BMC
Petit et al., 2002 Girls. White & Asian.
Age 10.0±0.6yrs
Randomized by school
Con = 25; Ex = 43
50-100 jumps and circuit training GRF = 3.5-5 bw;
3 times/week; 10mins/session; 7 months duration
NS
Van Langendonck et al., 2003 Girls.
Age 8.7±0.7yrs
Twin study
Con = 21; Ex = 21
Hopping and jumping exercises; 3 times/week; 10mins/session; 9 months duration PF + 2.5% BMC
Mackelvie et al., 2004 Boys. White & Asian.
Age 10.2±0.5yrs
Randomized by school
Con = 33; Ex = 31
50-100 jumps and circuit training GRF = 3.5-5 bw;
3 times/week;12mins/session; 20 months duration
FN + 4.3% BMC
Laing et al., 2005 Girls. White, Asian & black.
Age 6.0±1.6yrs.
No randomization
Con = 78; Ex = 65
Recreational gymnastics; 1 hour/week; 24 months duration LS+11.6% aBMD
Linden et al., 2006 Girls.
Age 7.8±0.6yrs
No randomization
Con = 50; Ex = 49
PE- Ball games, running and jumping; 200mins/week; 2 years duration TB + 0.6% aBMD
LS + 1.2% aBMD
LS + 3.8% BMC
Valdimarsson et al., 2006 Girls.
Age 7.8±0.6yrs
No randomization
Con = 50; Ex = 53
PE- Ball games, running and jumping; 5 times/week; 40mins/session; 1 year duration LS + 2.8% aBMD
LS + 4.7% BMC
Pubertal and adolescent Blimkie et al., 1996 Girls.
Age 16.2±0.2yrs
Randomized within school
Con = 16; Ex = 16
Resistance training, hydraulic machines; 13 exercises x 4 sets; 10-12 reps; 3 times/week; 6.5 months duration NS
Morris et al., 1997 Girls.
Age 9.5±0.9yrs
No randomization
Con = 33; Ex = 38
After school clubs of aerobics, step aerobics, soccer, dance, ball games and weight training; 3 times/week; 30mins/session; 10 months duration TB +3.5% aBMD
LS+4.8% aBMD
PF + 4.5% aBMD
FN + 12% aBMD
PF + 4.5% aBMD
TB + 12% BMC
LS + 7% BMC
FN + 10.4% BMC
PF + 11.9% BMC
Witzke and Snow 2000 Girls. White.
Age 14.6±0.5yrs
No randomization
Con = 28; Ex = 25
Resistance training and plyometrics; 3 times/week; 30-45mins/session; 9 months duration NS
Mackelvie et al., 2001 Girls. White & Asian.
Age 11.0±0.9yrs
Randomised by school
Con = 64; Ex = 43
50-100 jumps and circuit training GRF = 3.5-5 bw; 3 times/week; 10-12mins/session; 7 months duration LS + 8.2% aBMD
FN + 6.7% aBMD
LS 16.5% BMC
FN + 11.3% BMC
FN + 3.6% vBMD
Nichols et al., 2001 Girls.
Age 15.9±0.1yrs
Group randomized
Con = 21; Ex = 46
15 resistance exercises; 3 times/week; 30-45mins/session; 15 months duration FN + 2.3% aBMD
Kontulainen et al., 2002 Girls.
Age 12.8±1.5yrs
Group randomised
Con = 49; Ex = 50
Step aerobic and jumping program; 2 times/week; 50mins/sessions; 20 months duration. LS + 4.9% BMC
Petit et al., 2002 Girls. White & Asian.
Age 10.5±0.6yrs
Randomized by school
Con = 63;Ex = 43
5 diverse jumping exercises GRF = 3.5-5 bw; 3 times/week; 10mins/session; 7 months duration FN + 2.6% aBMD
IR + 1.7% aBMD
Iuliano-Burns et al., 2003 Girls. White & Asian
Age 8.8±0.1yrs
Randomized by group
4 groups of 16
Moderate impact skipping, hopping and jumping GRF = 2-4 bw; 3 times/week; 20mins/session; 8.5 months duration FN + 7.1% BMC
Mackelvie et al., 2003 Girls. White & Asian.
Age 9.9±0.6yrs
Randomized by school
Con = 43;Ex = 32
100 jumps and circuit training GRF = 3.5-5 bw;
3 times/week; 10mins/session; 20 months duration
LS + 41.7% BMC
FN + 24.8% BMC
Stear et al., 2003 Girls. White.
Age 17.3±0.3yrs
Randomized by group
Con = 66; Ex = 65
Exercise to music; 3 times/week; 45 mins/session; 15.5 months duration TB + 0.8% BMC
LS + 1.9% BMC
FN + 2.2% BMC
HIP + 2.7% BMC
TR + 4.8% BMC
Mckay et al., 2005 Girls and boys.
White & Asian.
Age 10.1±0.5yrs
Randomized by school
Con = 71;Ex = 51
Bounce at the Bell; 10 CMJ GRF = 5 bw; times/day; 3mins/session; 8 months duration PF + 2.0% BMC
TR + 27% BMC
Matthews et al., 2006 Girls. White & Asian.
Age 8-11 yrs
Randomized by school
Con = 61;Ex = 82
Ballet dancing; 4.5 hours/week to 7.0/hours week; 3 years duration TB + 1% BMC
LS + 0.6% BMC
FN + 4% BMC
Multiple maturity groups Bailey et al., 1999 Girls and boys.
Age 8–14yrs
53 girls; 60 boys Daily physical activity measured via questionnaire; 6 years duration Active boys had 9% and girls 17% > TB BMC
Heinonen et al., 2000 Girls. White.
Age 13.7±0.9yrs
No randomization
Con = 33;Ex = 25
Con = 29;Ex = 39
100-220 jumps, one and two footed from 30cm; 2 times/week; 20mins/sessions; 9 months duration LS +8.6% BMC
FN + 9.3% BMC
Sundberg et al., 2001 Girls and boys.
Age 16.0±0.3yrs
Randomized by school
Con =148;Ex = 80
Weight loaded activities such as running, jumping, gymnastics; 4 x 40mins/week PE in school; 4 years duration TB +3% aBMD
LS + 3% aBMD
FN + 9% aBMD
TB + 4% BMC
LS + 9% BMC
FN + 8% BMC
* % gained over exercise intervention in exercise group (after any statistical adjustments). Only significant results reported. Age reported as mean ± SD. Abbreviations: aBMD – areal bone mineral density; ANCOVA – Analysis of covariance; ANOVA – Analysis of Variance; BMC – Bone mineral content; bw – Body weight; CMJ – Counter movement jump; Con = Controls; Ex = Exercise; FN – Femoral neck; FS – Femoral shaft; GRF – Ground reaction force; GT – Greater trochanter; IT – Intertrochanteric region; LS – Lumbar spine; NS – Non significant findings; PE – Physical education; PF – Proximal femur; reps – repetitions; TB – Total body; TR – Trochanter; vBMD – Volumetric bone mineral density.