Table 1. The process of the study.
Intervention Immobilization Rehabilitation
Acute Phase Recovery Phase Maintenance Phase
Duration (1-2 weeks) (3-4 weeks) (5-6 weeks)
Cr supplement 5 days loading phase followed by a 37 days maintenance phase
Variables SLM Baseline R2 R4 R6
PFT R2 R4 R6
NRS Baseline R2 R4 R6
CK Baseline, 24, 48, 72, 96
NRS-numeric rating scale; SLM-segmental lean mass; PFT-plantar flexion torque; CK- creatine kinase), the duration of the creatine supplementation (Cr supplement), and the time of measurements (Baseline-prior the immobilization; R2 - after 2 weeks of the acute phase; R4 - after 2 weeks of the recovery phase; R6 - after 2 weeks of the maintenance phase; 24, 48, 72, and 96 hours after baseline.