Table 3.
Association analysis of the IL1B gene rs1143627 polymorphism with ACL rupture.
Model
ACLR (n=229)
%
CON (n=194)
%
OR
95% CI
p
*
Codominant
A/A
99
43.2
94
48.5
1.00
0.208/0.377
A/G
101
44.1
85
43.8
0.89
0.59
1.33
G/G
29
12.7
15
7.7
0.54
0.27
1.08
Dominant
A/A
99
43.2
94
48.5
1.00
0.283/0.366
A/G-G/G
130
56.8
100
51.5
0.81
0.55
1.19
Recessive
A/A-A/G
200
87.3
179
92.3
1.00
0.094/0.197
G/G
29
12.7
15
7.7
0.58
0.30
1.11
Overdominant
A/A-G/G
128
55.9
109
56.2
1.00
0.952/0.898
A/G
101
44.1
85
43.8
0.99
0.67
1.45
* after a slash p value adjusted for sex; OR – odds ratio, 95% CI – confidence intervals