Table 5.
Association analysis of the IL6R gene rs2228145 polymorphism with ACL rupture.
Model
ACLR (n=228)
%
CON (n=194)
%
OR
95% CI
p
*
Codominant
A/A
99
43.2
81
41.8
1.00
0.760/0.714
A/C
94
41.0
86
44.3
1.12
0.74
1.69
C/C
36
15.7
27
13.9
0.92
0.51
1.64
Dominant
A/A
99
43.2
81
41.8
1.00
0.759/0.677
A/C-C/C
130
56.8
113
58.2
1.06
0.72
1.56
Recessive
A/A-A/C
193
84.3
167
86.1
1.00
0.603/0.610
C/C
36
15.7
27
13.9
0.87
0.50
1.49
Overdominant
A/A-C/C
135
59.0
108
55.7
1.00
0.496/0.433
A/C
94
41.0
86
44.3
1.14
0.78
1.68
* after a slash p value adjusted for sex; OR – odds ratio, 95% CI – confidence intervals