Table 8.
Association analysis of the IL6 x IL6R interaction with ACL rupture (codominant model).
IL6
x
IL6R
IL6R
(rs2228145)
p
vs
CON
*
A/A
A/C
C/C
ACLR
CON
OR
95%
CI
ACLR
CON
OR
95%
CI
ACLR
CON
OR
95%
CI
IL6
(rs1800795)
G/G
29
30
1.00
NA
NA
23
26
1.09
0.51
2.33
8
5
0.60
0.18
2.06
0.818/
0.936
C/G
51
33
0.63
0.32
1.23
59
39
0.64
0.33
1.23
21
12
0.55
0.23
1.32
C/C
18
18
0.97
0.42
2.21
12
21
1.69
0.71
4.05
7
10
1.38
0.46
4.12
* after a slash p value adjusted for sex; OR – odds ratio, 95% CI – confidence intervals; NA – not applicable