Table 3. Allelic frequencies of the SNPs identified by comparison between elite endurance runners and controls. |
| References |
SNP |
Frequency of allele in elite endurance runners, % |
Frequency of
allele in controls, % |
P-value |
| Ahmetov et al., 2015 |
NFIA-AS2 rs1572312 C
TSHR rs7144481 C
RBFOX1 rs7191721 G |
95.5
25.7
58.6 |
88.8
17.4
56.3 |
0.007*
0.032*
0 .60 |
| Amir et al., 2007 |
ACE D rs4646994
ACE DD rs4646994 |
77.0
62.0 |
66.0
43.0 |
0.01*
0.004* |
| Ash et al., 2011 |
ACE I/D rs4646994
ACE A22982G rs4363 |
44.7
44.7 |
45.6
45.8 |
0.16
0.97 |
| Döring et al., 2010 |
HIF1A Pro582 rs11549465 C
HIF1A rs17099207 A
HIF1A rs1951795 C
HIF1A rs11158358 C/G
HIF1A rs2301113 A/C
HIF1A rs11549467 G/A |
84.0
9.2
67.7
25.3
33.5
3.2 |
75.0
4.9
62.2
27.0
32.9
1.6 |
0.017*
0.045*
0.038*
0.07
0.06
0.21 |
| He et al., 2015 |
PPARAGC1A rs4452416 T
PPARAGC1B rs2161257 G
NRF1 rs7794909 T
SIRT1 rs11596401 C |
17.2
39.6
9.6
87.2 |
13.1
33.6
5.8
83.3 |
0.035*
0.026*
0.007*
0.050* |
| Martinez et al., 2009 |
AQP1 rs1049305 C |
57.0 |
49.0 |
0.03* |
| Myerson et al., 1999 |
ACE I rs4646994 |
52.0 |
49.0 |
0.01* |
| Sawczuk et al., 2013 |
ADRA2A rs553668 C |
85.8 |
82.9 |
0.40 |
| Tobina et al., 2010 |
ACE I/D rs4646994 |
44.0 |
44.0 |
0.001* |
| Wolfarth et al., 2008 |
NOS3 Glu298Asp rs1799983 G/T
NOS3 (CA)n repeats 164 bp
NOS3 27-bp repeats 4B/4A |
41.0
24.1
25.0 |
47.0
16.7
25.0 |
0.27
0.01*
0.83 |
|
*Significant difference between elite endurance, including marathon runners, and controls at p < 0.05 level. |
|