Table 4. Mean ± SD reaction times (ms) for the ANAM protocol. Familiarization (ms) Pre-Fatigue (ms) Post-Fatigue (ms) p-Value SRT 234.4 ± 17.6 241.1 ± 24.0 232.0 ± 22.3 0.263 CDS 858.8 ± 146.7 590.6 ± 86.1 859.7 ± 89.9 0.406 PRO 510.9 ± 58.3 494.6 ± 61.1 500.6 ± 54.6 0.54 MTH 2253.7 ± 567.6 2518.2 ± 884.8 1885.2 ± 582.8* <0.001 CDD 881.1 ± 113.8 937.9 ± 139.2 1104.4 ± 294.0 0.078 GNG 296.0 ± 15.9 298.5 ± 12.1 285.9 ± 16.3* 0.031 SR2 235.5 ± 18.7# 252.0 ± 24.3 251.3 ± 23.5 0.042 # = (p< 0.05) from pre-fatigue and post-fatigue values. SRT = Simple Reaction Time ; CDS = Coded Substitution-Learning; PRO = Procedural Reaction Time; MTH = Mathematical Processing; CDD = Coded Substitution-Delay; GNG = Go/No-Go; SR2 = Simple Reaction Time 2. P-values were determined from repeated measures ANOVAs, * Indicates significant (p < 0.05) difference from pre-fatigue values as determined from post-hoc pairwise comparisons. SRT = Simple Reaction Time ; CDS = Coded Substitution-Learning; PRO = Procedural Reaction Time; MTH = Mathematical Processing; CDD = Coded Substitution-Delay; GNG = Go/No-Go; SR2 = Simple Reaction Time 2. P-values were determined from repeated measures ANOVAs, * Indicates significant (p < 0.05) difference from pre-fatigue values as determined from post-hoc pairwise comparisons. # = (p< 0.05) from pre-fatigue and post-fatigue values.