Table 2. Changes (mean ± SD) in plasma glutamic oxaloacetate transaminase activity (GOT, IU/L) and glutamic pyruvic transaminase activity (GPT, IU/L), potassium concentration (K, mEq/L), phosphorus (P, mg/dL), uric acid concentration (UA, mg/dL) and high sensitivity cardiac troponin T concentration (hsTnT, ng/L), and osmolality (Osm, mOsm/kg H2O)) at baseline, 1 hour after the first (1st), second (2nd) and third (3rd) Loughborough Intermittent Shuttle Test (LIST), and 1, 2, 3, 4 and 5 days after the 3rd LIST for the one (1d), two (2d), three (3d) and four (4d) days of rest between LISTs. C Measures Baseline 1 2 3 4 5 6 7 8 9 1d GOT 15±4 26±15* 66±40* 94±47* 127±59* 93±44* 59±37* 28±12* 17±6* 17±6* 2d 16±4 25±12* 64±28* 87± 38* 118±42* 86±37* 56±31* 24±9* 18±3* 18±3* 3d 14±3 27±21* 54±22* 53±20*#^ 59±16*#^ 46±15*#^ 33±8*#^ 18±8*#^ 10±6#^ 10±6#^ 4d 15±4 26± 13* 51±16* 45±13*#^†  40±17*#^†  31±10*#^†  24± 10*#^†  14±4#^†  12±4#^ 12±4#^ 1d GPT 16±5 25±13* 65±30* 89±37* 124±41* 87±31* 54±26* 32±11* 20±5* 20±5* 2d 16±6 23±0* 60±27* 84±38* 115±43* 85±33* 51±26* 26±12* 19±4* 19±4* 3d 16±4 27±6* 59±22* 63±21*#^ 70±23*#^ 56±20*#^ 42±13*^ 20±9*#^ 11±7#^ 11±7#^ 4d 17±5 28±11* 56±17* 50±14*#^†  45±21*#^†  32±14*#^†  23±10*#^†  15±5#^†  12±2#^ 12±2#^ 1d K 4.3±.2 4.6±.3* 4.8±.3* 5.1±.3* 5.1±.3* 4.8±.3* 4.6±.3* 4.5±.3* 4.3±.3* 4.3±.3* 2d 4.2±.3 4.6±.3* 4.9±.4* 5.1±.5* 4.9±.4* 4.7±.3* 4.5±.3* 4.3±.3* 4.2±.3 4.2±.3 3d 4.2±.2 4.7±.4* 4.8±.3* 4.6±.3*#^ 4.5±.2*#^ 4.3±.2*#^ 4.2±.2#^ 4.0±.1#^ 3.9±.1#^ 3.9±.1#^ 4d 4.2±.2 4.8±.5* 4.8±.3* 4.6±.2*#^ 4.4±.2*#^†  4.2±.2#^†  4.0±.2#^†  3.9±.2#^†  3.8±.2#^ 3.8±.2#^ 1d P 3.5±.4 3.9±.4* 4.2±.4* 4.6±.4* 4.5±.4* 4.2±.4* 4.0±.4* 3.8±.4* 3.7±.4* 3.7±.4* 2d 3.5±.3 3.9±.3* 4.3±.3* 4.6±.4* 4.4±.3* 4.1±.2* 4.0±.2* 3.7±.3* 3.6±.2* 3.6±.2* 3d 3.±.3 4.0±.3* 4.2±.3* 4.2±.0* #^ 4.0±.3*#^ 3.8±.3*#^ 3.7±.3*#^ 3.6±.3*# 3.5 ±.3 3.5±.3 4d 3.4±.4 4.0±.3* 4.2±.5* 4.2±.4*#^ 3.9±.4*#^ 3.7±.4*#^ 3.6±.4*#^ 3.5±.4# 3.4±.4 3.4±.4 1d UA 5.0±.6 5.5±.8* 5.6±.7* 5.8±.7* 5.7±.7* 5.6±.7* 5.4±.7* 5.2±.7* 5.1±.7* 5.1±.7* 2d 4.9±.6 5.4±.9* 5.7±.9* 5.8±.8* 5.6±.7* 5.4±.7* 5.3±.7* 5.1±.7* 5.0±.6* 5.0±.6* 3d 4.8±.9 5.4±.8* 5.6±.8* 5.4±.7* 5.3±.7* 5.1±.7* 4.9±.8 4.7±.8#^ 4.5±.8#^ 4.5±.8#^ 4d 4.8±.7 5.4±.9* 5.2±.8* 5.0±.7*#^ 4.8±.7*#^ 4.6±.7#^†  4.5±.7#^†  4.3±.7#^ 4.2± .7#^ 4.2±.7#^ 1d hsTnT 2.1±1.0 7.4±6.4* 9.8± 7.3* 15.7±15.5* 8.8± 6.4* 6.2±4.4* 4.9±3.9* 3.6±2.1* 2.4±.4* 2.4±.4* 2d 1.7±.5 5.9±5.1* 8.4±3.8* 10.2±3.0* 6.1 ±1.4* 4.5±1.1* 1.2±1.2* 2.0±.9* 1.8±.8 1.8±.8 3d 2.0±.7 6.8±1.2* 5.5±1.7*#^ 5.0±.9*#^ 4.3±1.8*#^ 2.6±.9*#^ 2.2±.8# 2.0±.8# 1.7±.6# 1.7±.6# 4d 1.8±.6 5.6±2.5* 4.2±1.4*#^†  3.7±2.0*#^†  3.1±1.3*#^†  2.3±1.2#^ 2.0±1.0# 1.9±.9# 1.6±.5# 1.6±.5# 1d Osm 282±5 298±5* 302±4* 305±7* 297±5* 289±3* 284±3* 282±5 282±5 282±5 2d 283±3 297±11* 300±9* 301±9* 291±2* 287±3* 284±3 283±3 283±3 283±3 3d 283±5 299±6* 298±6*# 294±6*#^ 286±5*#^ 285±5*#^ 284±5 284±5 283±5 283±5 4d 283±6 301±9* 297±7*# 292±7*#^ 285±5*#^ 283±6# 282±6 282±6 281±6 281±6 *: a significant (P<0.05) difference from the baseline value. #: significantly different from the 1d condition. ^: significantly different from the 2d condition. † : significantly different from the 3d condition.