Table 4. Biomarkers of oxidative (pre) and after (post) 3 weeks exercise training in normoxia (NT) and hypoxia (HT). |
| Variables |
NT,
n=12 |
HT,
n=12 |
Main
effects (p-value, ηp2) |
| Pre |
Post |
Pre |
Post |
Ox |
T |
Ex |
Ox*T |
Ox*Ex |
T*Ex |
Ox*T*Ex |
SOD
[U/gHb] |
rest |
1248.2
± 92.4 |
1215.1
± 78.0 |
1250.0
± 108.0 |
1152.5
± 115.5 |
0.233
(0.126) |
0.708
(0.031) |
0.001
(0.615) |
0.961
(0.000) |
0.008
(0.484) |
0.193
(0.148) |
0.498
(0.043) |
| max |
1195.2
± 59.5 |
1195.0
± 59.3 |
1195.0
± 68.9 |
1250.6
± 54.1 |
GPX
[U/gHb] |
rest |
47.0 ±
6.5 |
48.0 ±
8.5 |
48.1 ±
8.2 |
54.2 ±
6.1 |
0.008
(0.482) |
0.034
(0.347) |
0.000
(0.733) |
0.104
(0.222) |
0.175
(0.160) |
0.501
(0.042) |
0.147
(0.181) |
| max |
54.7
± 7.4 |
55.0
± 9.4 |
55.7
± 6.9 |
58.3
± 8.6 |
CAT
[U/gHb] |
rest |
214.9 ±
38.5 |
219.6 ±
33.0 |
224.3 ±
27.9 |
234.5 ±
38.6 |
0.228
(0.129) |
0.085
(0.246) |
0.000
(0.785) |
0.298
(0.098) |
0.692
(0.015) |
0.351
(0.079) |
0.804
(0.006) |
| max |
229.6
± 18.6 |
232.5
± 17.2 |
230.6
± 15.4 |
235.8
± 6.5 |
GSH
[μg/mgHb] |
rest |
2.9 ±
0.5 |
2.9 ±
0.7 |
2.9 ±
0.5 |
2.8 ±
0.5 |
0.365
(0.075) |
0.221
(0.133) |
0.020
(0.404) |
0.025
(0.379) |
0.010
(0.468) |
0.366
(0.075) |
0.092
(0.237) |
| max |
3.0
± 0.5 |
3.1
± 0.5 |
3.2
± 0.7 |
2.7
± 0.4# |
|
SOD-superoxide dismutase; GPX- glutathione peroxidase; CAT-catalase; GSH- reduced glutathione. Ox-oxygen conditions; T-training and Ex-exercise effects. Data are means and SD. |
#p < 0.05 significant differences between post - HT vs. post – NT. |
|