Journal of Sports Science and Medicine
Journal of Sports Science and Medicine
ISSN: 1303 - 2968   
Ios-APP Journal of Sports Science and Medicine
Androit-APP Journal of Sports Science and Medicine
©Journal of Sports Science and Medicine (2018) 17, 298 - 304

Research article
Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability
Patrick Dressler1, , Dominic Gehring1, Denise Zdzieblik1, Steffen Oesser2, Albert Gollhofer1, Daniel König1
Author Information
1 University of Freiburg, Department of Sport and Sport Science, Freiburg, Germany
2 CRI, Collagen Research Institute, Kiel, Germany

Patrick Dressler
✉ University of Freiburg, Department of Sport Science, Schwarzwaldstr. 175, 79117 Freiburg i. Br., Germany
Publish Date
Received: 24-10-2017
Accepted: 11-04-2018
Published (online): 14-05-2018
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Following an initial ankle sprain it is not unlikely that chronic ankle instability (CAI) will develop. CAI is associated with impaired perceived functional and mechanical properties of the ligaments. Nutritional supplementation with collagen peptides has been shown to improve the functional and mechanical properties of the connective tissue. The purpose of this study was to investigate the effectiveness of specific collagen peptide supplementation (SCP) to improve ankle stability in athletes with CAI. 50 male and female athletes with CAI completed a randomized, double-blinded and placebo-controlled study with a daily oral administration of either 5 g SCP or 5 g placebo (Maltodextrin) over a period of six months. Both, the Cumberland Ankle Instability Tool (CAIT) and the German version of the Foot and Ankle Ability Measure (FAAM-G) were used to measure the subjective perceived function of the ankle. Additionally, the mechanical stability was determined by measuring the ankle stiffness by an ankle arthrometer. Finally, a three-month follow-up was performed. ANOVA analysis indicated that the subjective ankle stability was improved in both the CAIT (p < 0.001) and the FAAM-G (p < 0.001) following SCP supplementation compared with placebo. No significant changes between the groups were detected in the results of the ankle arthrometer. After six month the subjective report of the ankle stability function significantly improved and the three month follow-up revealed a significant decline in the number of ankle joint injuries (p < 0.05). These data support the concept that specific collagen peptide supplementation in athletes with chronic ankle instability results in significant improvements in subjective perceived ankle stability. The reduction in the re-injury rate of ankle sprains in the follow-up period suggests that these findings have clinical relevance.

Key words: Ankle sprain, collagen, nutrition, ligaments

           Key Points
  • Collagen peptides significantly improved subjective perceived function of the ankle in activities of daily living and sports exercise.
  • Decreases in ankle sprains and the risk of ankle injuries were shown in a three-month follow-up period.
  • These first results need to be confirmed by further investigations.
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