Journal of Sports Science and Medicine
Journal of Sports Science and Medicine
ISSN: 1303 - 2968   
Ios-APP Journal of Sports Science and Medicine
Androit-APP Journal of Sports Science and Medicine
©Journal of Sports Science and Medicine (2021) 20, 448 - 456   DOI:

Research article
Augmentation Index Predicts the Sweat Volume in Young Runners
Yen-Yu Liu1,2,3, Chung-Lieh Hung2,3,4, Fang-Ju Sun4,5,6, Po-Han Huang7, Yu-Fan Cheng8, Hung-I Yeh2,3,4, 
Author Information
1 Department of Critical Care Medicine, MacKay Memorial Hospital, Taipei, Taiwan
2 Cardiovascular Division, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan
3 Institute of Biomedical Sciences, Mackay Medical College, New Taipei City, Taiwan
4 Mackay Junior College of Medicine, Nursing and Management, Taipei, Taiwan
5 Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan
6 Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
7 General Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan
8 General Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan

Hung-I Yeh
✉ Cardiovascular Center and Division of Cardiology, Mackay Memorial Hospital, 92, Sec 2, Zhongshan North Road, Taipei 10449, Taiwan
Publish Date
Received: 02-04-2021
Accepted: 13-05-2021
Published (online): 25-05-2021
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Sweating during exercise is regulated by objective parameters, body weight, and endothelial function, among other factors. However, the relationship between vascular arterial stiffness and sweat volume in young adults remains unclear. This study aimed to identify hemodynamic parameters before exercise that can predict sweat volume during exercise, and post-exercise parameters that can be predicted by the sweat volume. Eighty-nine young healthy subjects (aged 21.9 ± 1.7 years, 51 males) were recruited to each perform a 3-km run on a treadmill. Demographic and anthropometric data were collected and hemodynamic data were obtained, including heart rate, blood pressure and pulse wave analysis using non-invasive tonometry. Sweat volume was defined as pre-exercise body weight minus post-exercise body weight. Post-exercise hemodynamic parameters were also collected. Sweat volume was significantly associated with gender, body surface area (BSA) (b = 0.288, p = 0.010), peripheral systolic blood pressure (SBP), peripheral and central pulse pressure (PP), and was inversely associated with augmentation index at an HR of 75 beats/min (AIx@HR75) (b = -0.005, p = 0.019) and ejection duration. While BSA appeared to predict central PP (B = 19.271, p ≤ 0.001), central PP plus AIx@HR75 further predicted sweat volume (B = 0.008, p = 0.025; B = -0.009, p = 0.003 respectively). Sweat volume was associated with peripheral SBP change (B = -17.560, p = 0.031). Sweat volume during a 3-km run appears to be influenced by hemodynamic parameters, including vascular arterial stiffness and central pulse pressure. Results of the present study suggest that vascular arterial stiffness likely regulates sweat volume during exercise.

Key words: Exercise, sweat, body surface area, augmentation index, hemodynamic parameters

           Key Points
  • The body surface area and the augmentation index adjusted for heart rate (AIx@HR75) were able to predict sweat production during exercise
  • Sweat volume in such an exercise also predicts the changes in peripheral systolic blood pressure (SBP).
  • The vascular arterial stiffness and the central pulse pressure (PP) likely regulate sweat volume during exercise.
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